As AI moves beyond language, new foundation models are emerging that predict, design, and translate materials into manufacturable processes. This panel brings together academia, industry, and infrastructure partners to discuss physics-focused foundational models, their responsible applications in biology, energy, and manufacturing, and the national strategies needed for sovereign capability. Attendees will see a live Physics model demo, explore technical and ethical challenges, policy frameworks, and map pathways for industrial validation, pilot deployment, and collaborative scaling.